I've had similar issues. Mine were related to the Sample Rate of Windows being consistent with the sample rate of my AudioFuse Studio. Once I made sure my DAW, AudioFuse Control Center, and Windows are all at a 48k sample rate, things work fine (44k should work too but I record at 48k). I can play my different web browser audio sources like YouTube at the same time as a stand alone piano vst plugin, and also open my DAW and listen to that sound too and all will play at the same time without the clicking or pauses. Hope this helps!