I haven't jumped in completely but I have the i5 64, quad core and it seems to be working fine.
I did have one issue when I took the dongle out and loaded up ableton. it appeared as if it vanished. I think even the uninstall option was gone too. I reinstalled the plug-in again, kept the dongle in and it seems to be ok.
I read in the forum where someone wrote and said they has issues loading up logic if the dongle wasn't plugged into the computer. I would strongly advise having a home studio and perhaps one for shows which you aren't live expecting things to work perfectly.. perhaps using the stage computer for shows using loops ect...
I think as long as you keep the dongle in your computer you should be fine has been my experience up until this point.