I've just spent a while with this. There are a few possibilities, though I'm not very familiar with the CS80V.
One question before anything else: is the multi-mode panel at the top of the synth open or closed in your version of the patch?
It was closed in my version, and when I opened it I got something that sounds like what you're describing. That was after trying a lot of other things to try to replicate your problem, so it's now too late at night to work out what's happening there and refine it, but if that section is open you may find that's the key to your problem - either just close it, or try making some adjustments.
The popping sound is probably CPU overload - it often is. If editing synth settings doesn't help, and if the problem coincides with the CPU percentage readout going into high figures, try the file menu - preferences - sample rate and experiment with other settings.
If it isn't that, and if someone else doesn't come up with a solution, then feel free to email me your version of the patch in question. It may differ from mine.
With any luck someone more knowledgeable than me on the CS80 will contribute to this, but if not then maybe that may be of some help?