DAW = Studio One 5.2
When I use the sequencer with a VSTi and at the same time adjust i.e. the Filter on that VSTi via the microfreak cutoff knob, then the MIDI Studio One receives glitches out. It is most noticable at faster sequences (1/16th) and it almost sound like a weird swing that is not intended.
Check the Picture for the recorded MIDI of that glitch. The first is the glitched MIDI and the second is without adjusting any parameters.