Hi tobyricketts,
another user have a similar issue , as i already answered to him, maybe this answer will give you some ideas
"i have a few clues here :
can you tell me what exact version of AudioFuse control center you are using?
if you are using a DAW for recording , mixing tracks etc... you are working on a certain samplerate between 44.1 and 192khz,
now imagine you leave your DAW open and then you use another application to play an audiofile
When playing the audio file, AudioFuse will try to set it's samplerate according to the setting in AUdio device manager advanced preferences, but as the DAW is still open , it simply can't be done.
i.e i was working in Live on a project at 96khz, but the samplerate of windows is on 44,1khz. i leave live open and try to play a video on youtube -> video doesn't load, progress bar is stuck etc...
so you can maybe :
ensure you don't have 2 audio applications running in the same time (even if audio is not playing)
or
set your system sample rate according to the one you are commonly using when working on a DAW
you can set it by right click on the speaker icon bottom right of your desktop, click on playback devices , set "MASTER" as default playback device, you can access "MASTER" properties , advanced, and set the sample rate here."
hope it helps,
best