This may be unrelated, but I occasionally have similar problems. I find that Analog lab is very fussy about what USB devices are connected to my PC. I have a Keylab 49 and a Novation Nova. Both work fine with Analog Lab. However, if I close the program with both connected, and then launch next time with only one device connected, the program crashes - turning on the 'missing' device before relaunching seems to cure it on most occasions. However, I find that sometimes the only thing that works is to start Windows in safe mode, then launch Analog lab and check the midi settings (making sure any connected devices are set).
Try safe mode - it seems to flush out some blockages.