Hi again,
In generel i suggest you read documentation. It does'nt look like you have read about setting up devices in Studio One.
Your issues seem to have nothing to do with minilab MK2.
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When you set up a external device in Studio One, then keep in mind, that you in the "Recieve From" tell Studio One which device that setup will recieve from. In the "Send To" you set the device that Studio One will send to.
I suggest you in the Send either pick Minilab MK2 or None.
Also Check the Split Channels. This will enable you too select Midi Channels like i suggested in my first post.
Select ALL for midi channelss to use.
That will set up Minilab as a input device.
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Then i see you use your Audio interface as Midi interface too.
So try this: Add a NEW INSTRUMENT in Studio Ones device setup.
Select your interface in the Send and None in the Recieve.
Check the "Send MIDI Clock", the "Use MIDI Clock Start" and perhaps the "Send MIDI Timecode".
Select ALL for midi channels to use.
That will setup your interface as a output device.
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Now create a Instrument track.
Because you have selected "Split Channels" for you Minilab MK2 setup, you can select Minilab as input device (instead of "All Inputs") and after that you will be able to select a midi channel to use for that track.
As Output for the track you select your interface. You will then also be able to select a midi channel for that.
That will create the specific Routing. Just be sure the midi channels correspond to the instrument you send to.
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To record the sound from your external sound device you shall connect the instrument/ mixer audio outputs to your audio interface.
Then create a Audio track in Studio One and select the audio interface inputs you use as input for the track.
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I don't use external sound sources, but i think the above is a way to make it work.
But also check out the "Pipeline" in Studio One, in case that can be useful for you.
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You can find informations about all this in Presonus support pages i believe. And i also believe your Presonus audio interface have informations about this.
There are also informations and video tutorials to find on the web i believe. just search for it.
Also Presonus have a user forum, where you can ask questions about Studio One and your interface.
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To check if Minilab MK2 work with your sound units, then i suggest you connect the 5 pin midi cable directly from your minilab to your sound units.
In generel it can be good to start with the simple, and take it step by step.